Spicy Cajun Chicken Alfredo

Featured in: Family Dinner Plates

This dish features tender chicken breasts seasoned with Cajun spices, pan-seared to a golden brown. The fettuccine is cooked al dente and coated in a rich Alfredo sauce made from butter, garlic, heavy cream, Parmesan, smoked paprika, and optional chili flakes. The combination brings a perfect balance of creamy richness and bold heat. Garnished with fresh parsley and extra Parmesan, it’s a satisfying and flavorful meal suitable for spice enthusiasts seeking a comforting pasta experience.

Updated on Sat, 15 Nov 2025 11:20:00 GMT
A plate of creamy Spicy Cajun Chicken Alfredo with tender, seasoned chicken and parsley. Pin It
A plate of creamy Spicy Cajun Chicken Alfredo with tender, seasoned chicken and parsley. | sweetbatata.com

A bold, creamy pasta dish featuring tender Cajun-spiced chicken tossed with fettuccine in a rich Alfredo sauce. This is perfect for spice lovers looking for comfort food with a kick.

I made this Spicy Cajun Chicken Alfredo for a family game night and it disappeared in minutes. The creamy sauce mellowed the heat, making it a favorite with both spice aficionados and those who usually avoid spicy dishes.

Ingredients

  • Boneless, skinless chicken breasts: 2 large
  • Cajun seasoning: 2 tablespoons
  • Olive oil: 1 tablespoon
  • Fettuccine: 340 g (12 oz)
  • Unsalted butter: 2 tablespoons
  • Garlic: 3 cloves, minced
  • Heavy cream: 1 cup (240 ml)
  • Parmesan cheese: 1 cup (100 g), freshly grated
  • Smoked paprika: 1/2 teaspoon
  • Chili flakes: 1/2 teaspoon (optional, for extra heat)
  • Salt and black pepper: to taste
  • Chopped fresh parsley: 2 tablespoons, for garnish
  • Extra grated Parmesan cheese: for garnish

Instructions

Cook Pasta:
Boil fettuccine in salted water until al dente. Reserve 1/2 cup pasta water, drain, and set aside.
Season and Sear Chicken:
Pat chicken dry, coat with Cajun seasoning, and cook in olive oil over medium-high heat for 5-6 min per side until golden and cooked through. Rest for 5 min, then slice thinly.
Make Alfredo Sauce:
In the same skillet, reduce heat to medium, melt butter and sauté garlic for 1 min until fragrant.
Finish Sauce:
Add heavy cream, smoked paprika, and chili flakes. Simmer, then whisk in Parmesan until smooth. Season with salt and pepper.
Toss Pasta:
Combine pasta and sauce, toss to coat. Add reserved pasta water as needed for desired consistency.
Serve:
Top pasta with sliced chicken, parsley, and extra Parmesan. Serve immediately.
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When we enjoy this for dinner together, the spicy aroma always brings everyone to the table quickly. It is especially good for cozy evenings where everyone helps themselves straight from the skillet.

Required Tools

Large pot, skillet, tongs, chef's knife, cutting board, measuring cups and spoons.

Allergen Information

Contains dairy (cream, butter, Parmesan), gluten (fettuccine), and may contain allergens in Cajun seasoning. Always check ingredient labels for cross-contamination.

Nutritional Information

Per serving: Calories 610, Total Fat 27 g, Carbohydrates 54 g, Protein 38 g.

Tender Cajun-spiced chicken and rich Alfredo sauce coat fettuccine in this Spicy Cajun Chicken Alfredo. Pin It
Tender Cajun-spiced chicken and rich Alfredo sauce coat fettuccine in this Spicy Cajun Chicken Alfredo. | sweetbatata.com

This spicy Cajun chicken Alfredo is sure to become a household favorite. Serve it hot and watch everyone reach for seconds.

Recipe Questions & Answers

How do I ensure chicken stays tender and juicy?

Pat the chicken dry and coat evenly with Cajun seasoning before cooking. Sear over medium-high heat for 5-6 minutes per side, allowing it to rest before slicing to retain juices.

Can I substitute fettuccine with other pastas?

Yes, penne or linguine work well as alternatives, maintaining sauce adherence and texture.

How can I adjust the spice level?

Increase Cajun seasoning or add more chili flakes for extra heat, or reduce these for a milder flavor.

What can I use instead of heavy cream?

Half-and-half can be used for a lighter sauce, though it will yield a less rich texture.

How to achieve a silky sauce consistency?

Reserve some pasta water after cooking and add a little at a time to the sauce while tossing the pasta to smooth and thin the sauce.

Spicy Cajun Chicken Alfredo

Cajun-seasoned chicken combined with creamy Alfredo sauce and fettuccine for a bold dish.

Prep Time
15 min
Cook Time
25 min
Overall Time
40 min
Created by Nora James


Skill Level Medium

Cuisine American (Cajun-inspired, Italian-American)

Makes 4 Portions

Dietary Details None specified

What You'll Need

Chicken

01 2 large boneless, skinless chicken breasts
02 2 tablespoons Cajun seasoning
03 1 tablespoon olive oil

Pasta

01 12 ounces fettuccine

Alfredo Sauce

01 2 tablespoons unsalted butter
02 3 cloves garlic, minced
03 1 cup heavy cream (240 ml)
04 1 cup freshly grated Parmesan cheese (100 g)
05 1/2 teaspoon smoked paprika
06 1/2 teaspoon chili flakes (optional)
07 Salt and black pepper, to taste

Garnishes

01 2 tablespoons chopped fresh parsley
02 Extra grated Parmesan cheese

Cooking Steps

Step 01

Cook fettuccine: Boil salted water and cook fettuccine according to package instructions until al dente. Reserve 1/2 cup pasta water, then drain and set aside.

Step 02

Prepare chicken: Pat chicken breasts dry and evenly coat with Cajun seasoning.

Step 03

Cook chicken: Heat olive oil in a large skillet over medium-high heat. Sear chicken for 5-6 minutes per side until fully cooked and golden brown. Remove from skillet, rest 5 minutes, then slice thinly.

Step 04

Sauté garlic: Reduce heat to medium, add butter to the same skillet, and sauté minced garlic for 1 minute until fragrant.

Step 05

Create Alfredo sauce: Stir in heavy cream, smoked paprika, and chili flakes. Simmer gently, then whisk in Parmesan cheese until smooth. Season with salt and black pepper.

Step 06

Combine pasta and sauce: Add cooked fettuccine to the sauce, tossing to coat evenly. If necessary, add reserved pasta water gradually to achieve desired sauce consistency.

Step 07

Assemble and garnish: Top pasta with sliced Cajun chicken. Garnish with chopped parsley and extra Parmesan. Serve immediately.

Equipment Needed

  • Large pot
  • Large skillet
  • Tongs
  • Chef's knife
  • Cutting board
  • Measuring cups and spoons

Allergy Notice

Check each ingredient for allergens and reach out to a healthcare professional if you have concerns.
  • Contains dairy (cream, butter, Parmesan)
  • Contains gluten (fettuccine)
  • May contain mustard or celery from Cajun seasoning

Nutrition Information (per portion)

Sweetbatata only offers this for informational use. Please don't treat it as personalized medical advice.
  • Caloric Value: 610
  • Fats: 27 g
  • Carbohydrates: 54 g
  • Proteins: 38 g